PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35035665-0 2022 Celastrol Protects against Cerebral Ischemia/Reperfusion Injury in Mice by Inhibiting Glycolysis through Targeting HIF-1alpha/PDK1 Axis. celastrol 0-9 pyruvate dehydrogenase kinase, isoenzyme 1 Mus musculus 126-130 35035665-11 2022 Moreover, celastrol inhibited the I/R-induced upregulation of HIF-1alpha and PDK1. celastrol 10-19 pyruvate dehydrogenase kinase, isoenzyme 1 Mus musculus 77-81 35035665-14 2022 Taken together, these results suggested that celastrol protected against cerebral I/R injury through inhibiting glycolysis via the HIF-1alpha/PDK1 axis. celastrol 45-54 pyruvate dehydrogenase kinase, isoenzyme 1 Mus musculus 142-146