PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34428765-11 2021 In addition to that, Celastrol treatment can attenuate cell apoptosis and fibrosis of cardiomyocytes and elevate Bcl-2 expression. celastrol 21-30 BCL2, apoptosis regulator Rattus norvegicus 113-118 32307774-9 2020 Moreover, Cel exhibited the ability to antagonize HG-induced cardiomyocyte apoptosis and suppress the elevated Bax/Bcl-2 ratio elicited by HG stimulation. celastrol 10-13 BCL2, apoptosis regulator Rattus norvegicus 115-120 27181068-9 2016 Meanwhile, Celastrol suppressed the expression of the protein MDM2, activated the intrinsic mitochondrial apoptosis pathway induced by p53, inhibited anti-apoptotic Bcl-2 and Bcl-xl, induced the pro-apoptotic Bax, cytochrome C, PARP and caspases. celastrol 11-20 BCL2, apoptosis regulator Rattus norvegicus 165-170