PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16929507-0 2007 Effects of tripterine on mRNA expression of TGF-beta1 and collagen IV expression in BW F1 mice. celastrol 11-21 transforming growth factor, beta 1 Mus musculus 44-53 25076938-15 2014 Furthermore, celastrol suppressed TGF-beta1 induced EMT in thyroid cancer cells and may have therapeutic potential. celastrol 13-22 transforming growth factor, beta 1 Mus musculus 34-43 16929507-6 2007 Tripterine decreased urine protein excretion and the level of serum anti-dsDNA antibodies and also suppressed the expression of collagen type IV and TGF-beta1 mRNA in the murine kidney tissue. celastrol 0-10 transforming growth factor, beta 1 Mus musculus 149-158 12133425-4 2002 RESULTS: (1) Tripterine suppressed the development of proteinuria, decreased the level of serum anti-dsDNA antibodies, reduced the expressions of collagen type IV, fibronectin, TIMP-1, TIMP-2, TGF-beta(1) and improved the expressions of MMP-1, -2 in the murine kidney. celastrol 13-23 transforming growth factor, beta 1 Mus musculus 193-204 30798158-7 2019 RESULTS: C57BL/6 mice treated with CLT from 1 day post infection showed decreased disease, IL-1beta, TNF-alpha, IL-10, TGF-beta, MIP-2 and LOX-1 levels. celastrol 35-38 transforming growth factor, beta 1 Mus musculus 119-127 29789558-9 2018 Moreover, UUO- or TGF-beta1-induced activation of the pro-fibrotic factor SMAD family member 3 (Smad3) was markedly inhibited by celastrol. celastrol 129-138 transforming growth factor, beta 1 Mus musculus 18-27 27160852-15 2016 Celastrol attenuated miR-21 up-regulation by TGF-beta1 and decreased elevated p-ERK/ERK levels in CFs transfected with miR-21. celastrol 0-9 transforming growth factor, beta 1 Mus musculus 45-54 23637966-10 2013 Celastrol treatment significantly lowered mesangial expansion and suppressed type IV collagen, PAI-1 and TGFbeta1 expressions in renal tissues. celastrol 0-9 transforming growth factor, beta 1 Mus musculus 105-113