PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32958515-4 2020 The highest-ranked drug was the macrolide antibiotic Clarithromycin, which has previously been reported to have anti-inflammatory effects in aseptic conditions.Clarithromycin"s effects were validated in several experiments: it influenced NF-kappaB mediated transcription in murine peritoneal macrophages and intestinal enteroids; it suppressed NF-kappaB protein shuttling in murine reporter enteroids; it suppressed NF-kappaB (p65) DNA binding in the small intestine of mice exposed to LPS, and it reduced the severity of dextran sulphate sodium-induced colitis in C57BL/6 mice. dextran sulphate sodium 522-545 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 238-247 29710547-0 2018 NF-kappaB and Nrf2 pathways contribute to the protective effect of Licochalcone A on dextran sulphate sodium-induced ulcerative colitis in mice. dextran sulphate sodium 85-108 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 0-9 18495601-1 2008 OBJECTIVE: To investigate the changes in the activity of nuclear factor-kappaB (NF-kappa B) in mice with dextran sulphate sodium (DSS)-induced rat colitis and its modulalorg effect on intercellular adhesion molecule-1 (ICAM-1) expression. dextran sulphate sodium 105-128 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 57-78 18495601-1 2008 OBJECTIVE: To investigate the changes in the activity of nuclear factor-kappaB (NF-kappa B) in mice with dextran sulphate sodium (DSS)-induced rat colitis and its modulalorg effect on intercellular adhesion molecule-1 (ICAM-1) expression. dextran sulphate sodium 105-128 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 80-90