PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34081797-8 2021 Other experiments indicated that up-regulation of each of miRNA-125a-5p or miRNA-145 inhibited cell growth, induced apoptosis, and markedly decreased the IC50 value of erlotinib in A549 lung cancer cells(P<0.05). Erlotinib Hydrochloride 168-177 microRNA 145 Homo sapiens 75-84 34081797-10 2021 Both miRNA-125a-5p and miRNA-145 suppress the expression of EGFR gene Down-regulation of EGFR enhances the proliferation of the A549 lung cancer cells MiRNA-125a-5p and miRNA-145 reduce the erlotinib resistance in A549 cells Sensitization effects of miRNAs is linked to the enhancement of apoptosis This article is protected by copyright. Erlotinib Hydrochloride 192-201 microRNA 145 Homo sapiens 23-32 34081797-10 2021 Both miRNA-125a-5p and miRNA-145 suppress the expression of EGFR gene Down-regulation of EGFR enhances the proliferation of the A549 lung cancer cells MiRNA-125a-5p and miRNA-145 reduce the erlotinib resistance in A549 cells Sensitization effects of miRNAs is linked to the enhancement of apoptosis This article is protected by copyright. Erlotinib Hydrochloride 192-201 microRNA 145 Homo sapiens 171-180 25192889-12 2014 Increased miRNA-145 levels can predict overall survival, progression-free survival and excellent response rate to erlotinib. Erlotinib Hydrochloride 114-123 microRNA 145 Homo sapiens 10-19