PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25192889-7 2014 As a result, erlotinib is associated with a significant improvement in overall survival (P=0.0075, cohort 1; P=0.0372, cohort 2) and disease progression (P=0.6929, cohort 1; P=0.3347, cohort 2) in patients with reduced miRNA-21 expression. Erlotinib Hydrochloride 13-22 microRNA 21 Homo sapiens 219-227 26531758-8 2016 Moreover, miR-21, EGF and TGF-beta combined to markedly increase cancer cell invasion and migration, and this effect was blocked by the combination of erlotinib (an EGF receptor kinase inhibitor) and SB505124 (a type I TGF-beta receptor inhibitor). Erlotinib Hydrochloride 151-160 microRNA 21 Homo sapiens 10-16 25192889-11 2014 In conclusion, lung adenocarcinoma patients with reduced miRNA-21 expression exhibit longer overall survival and a poor response rate to erlotinib. Erlotinib Hydrochloride 137-146 microRNA 21 Homo sapiens 57-65