PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34552882-0 2021 Overexpression of Circular RNA circ_0013587 Reverses Erlotinib Resistance in Pancreatic Cancer Cells Through Regulating the miR-1227/E-Cadherin Pathway. Erlotinib Hydrochloride 53-62 microRNA 1227 Homo sapiens 124-132 34552882-12 2021 Rescue assays highlighted that circ_0013587 reversed erlotinib resistance in pancreatic cancer cells by increasing E-cadherin levels through reducing the expression of miR-1227. Erlotinib Hydrochloride 53-62 microRNA 1227 Homo sapiens 168-176 34552882-14 2021 Conclusions: Our results demonstrated that down-regulation of circ_0013587 contributes to acquired resistance to erlotinib in pancreatic cancer cells through mediating the miR-1227/E-cadherin pathway and that circ_0013587 is a potential target molecular to overcome erlotinib resistance. Erlotinib Hydrochloride 113-122 microRNA 1227 Homo sapiens 172-180