PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24957319-0 2014 Anti-Bv8 antibody and metronomic gemcitabine improve pancreatic adenocarcinoma treatment outcome following weekly gemcitabine therapy. gemcitabine 114-125 prokineticin 2 Mus musculus 5-8 24957319-5 2014 Furthermore, Bv8 is highly expressed in MDSCs colonizing pancreatic tumors in mice treated with weekly gemcitabine compared to MC gemcitabine or the combination of the two regimens. gemcitabine 103-114 prokineticin 2 Mus musculus 13-16 24957319-6 2014 Blocking Bv8 with antibodies in weekly gemcitabine-treated mice results in a significant reduction in tumor regrowth, angiogenesis, and metastasis. gemcitabine 39-50 prokineticin 2 Mus musculus 9-12 24957319-7 2014 Overall, our results suggest that pro-tumorigenic effects induced by weekly gemcitabine are mediated in part by MDSCs expressing Bv8. gemcitabine 76-87 prokineticin 2 Mus musculus 129-132 24957319-8 2014 Therefore, both Bv8 inhibition and MC can be used as legitimate "add-on" treatments for preventing post-chemotherapy pancreatic cancer recurrence, progression, and metastasis following weekly gemcitabine therapy. gemcitabine 192-203 prokineticin 2 Mus musculus 16-19