PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33468723-4 2021 Moreover, the expression of miR-141 in MDA-MB-436 cells treated with the PARP-1 inhibitor together with gemcitabine increased more than 10 times; additionally, the expression of miR-205 increased more in the context of combination therapy versus single exposure to olaparib. gemcitabine 104-115 microRNA 205 Homo sapiens 178-185 28719220-2 2017 We previously demonstrated that the combination of GEM and miR-205 provides an effective therapeutic strategy to sensitize GEM-resistant pancreatic cancer cells. gemcitabine 123-126 microRNA 205 Homo sapiens 59-66 24147037-0 2013 miR-29b, miR-205 and miR-221 enhance chemosensitivity to gemcitabine in HuH28 human cholangiocarcinoma cells. gemcitabine 57-68 microRNA 205 Homo sapiens 9-16 23073476-3 2013 Gemcitabine resistant MIA PaCa-2 cells possessed distinct ALDH-positive CSC fraction expressing stem cell markers OCT3/4 and CD44 and chemoresistance marker class IIIbeta-tubulin (TUBB3) which decreases on transfection with miR-205 resulting in the restoration of chemosensitivity to gemcitabine. gemcitabine 0-11 microRNA 205 Homo sapiens 224-231 32869841-11 2020 Additionally, the overexpression of miR-205-5p attenuated drug resistance to gemcitabine but promoted the gemcitabine-induced cell apoptosis by inhibiting the PRKCE in-vivo. gemcitabine 77-88 microRNA 205 Homo sapiens 36-43 32869841-11 2020 Additionally, the overexpression of miR-205-5p attenuated drug resistance to gemcitabine but promoted the gemcitabine-induced cell apoptosis by inhibiting the PRKCE in-vivo. gemcitabine 106-117 microRNA 205 Homo sapiens 36-43 31602229-0 2019 miR-205-5p downregulation decreases gemcitabine sensitivity of breast cancer cells via ERp29 upregulation. gemcitabine 36-47 microRNA 205 Homo sapiens 0-7 31602229-8 2019 Overexpression of miR-205-5p significantly augmented cytotoxicity effects of gemcitabine treatment in MDA-MB-231 and BT549 cells. gemcitabine 77-88 microRNA 205 Homo sapiens 18-25 31602229-11 2019 Additionally, following the established gemcitabine-resistant MDA-MB-231 cells (MDA-MB-231/GEM), ERp29 and HSP27 expression was upregulated and miR-205-5p was downregulated compared with parental cells. gemcitabine 40-51 microRNA 205 Homo sapiens 144-151 31602229-12 2019 Overexpression of miR-205-5p reversed gemcitabine resistance in MDA-MB-231/GEM cells. gemcitabine 38-49 microRNA 205 Homo sapiens 18-25 31602229-13 2019 In conclusion, the present study indicated that miR-205-5p may inhibit gemcitabine resistance in breast cancer cells via inhibition of ERp29 expression. gemcitabine 71-82 microRNA 205 Homo sapiens 48-55