PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30721106-0 2019 Detection of hemophagocytic extremely multinucleated giant plasma cells after rituximab/low-dose lenalidomide treatment in CD20+ multiple myeloma. Lenalidomide 97-109 keratin 20 Homo sapiens 123-127 31406628-3 2019 Furthermore, we investigated if lenalidomide, a potential sensitizer to anti-CD20 treatment, could prevent an inhibitory effect of ibrutinib. Lenalidomide 32-44 keratin 20 Homo sapiens 77-81 26002964-7 2015 Of particular clinical importance, lenalidomide also allowed NK cells to be activated by lower doses of rituximab, an anti-CD20 monoclonal antibody (mAb) widely used to treat B-cell malignancies. Lenalidomide 35-47 keratin 20 Homo sapiens 123-127 27980307-4 2016 Furthermore, some targeting drugs, such as lenalidomide, bortezomib and ibrutinib, directly or indirectly affect CD20 protein expression. Lenalidomide 43-55 keratin 20 Homo sapiens 113-117 25632047-1 2015 PURPOSE: Lenalidomide, an immunomodulatory agent that enhances antibody-dependent cell-mediated cytotoxicity, has the potential to synergize with rituximab, an anti-CD20 mAb. Lenalidomide 9-21 keratin 20 Homo sapiens 165-169 25547653-0 2015 Lenalidomide differently modulates CD20 antigen surface expression on chronic lymphocytic leukemia B-cells. Lenalidomide 0-12 keratin 20 Homo sapiens 35-39 18772452-0 2008 Lenalidomide down-regulates the CD20 antigen and antagonizes direct and antibody-dependent cellular cytotoxicity of rituximab on primary chronic lymphocytic leukemia cells. Lenalidomide 0-12 keratin 20 Homo sapiens 32-36 22171982-3 2012 Lenalidomide, an immunomodulator, is clinically effective in CLL and can enhance the anti-CLL effects of CD20 targeting monoclonal antibody, rituximab. Lenalidomide 0-12 keratin 20 Homo sapiens 105-109 25313353-9 2014 Lenalidomide also upregulated CD20 expression on leukemia cells and, accordingly, it had a synergistic effect with rituximab on promoting antibody-dependent cell-mediated cytotoxicity against primary leukemia cells. Lenalidomide 0-12 keratin 20 Homo sapiens 30-34 18772452-2 2008 The anti-CD20 antibody rituximab is active in CLL and represents a rational agent to combine with lenalidomide. Lenalidomide 98-110 keratin 20 Homo sapiens 9-13 18772452-4 2008 In contrast to previous reports using CD20-positive lymphoma cell lines, lenalidomide down-regulated CD20 surface antigen expression in CLL patient cells via enhanced internalization, without influencing transcription. Lenalidomide 73-85 keratin 20 Homo sapiens 101-105 18772452-6 2008 In addition, CD20 surface antigen down-modulation by lenalidomide in CLL was accompanied by diminished rituximab-mediated apoptosis and ADCC. Lenalidomide 53-65 keratin 20 Homo sapiens 13-17 18772452-8 2008 In addition, they suggest that lenalidomide therapy might be useful to enhance targeted delivery of RNAi-based therapies using CD20 immunoliposomes in B-cell malignancies. Lenalidomide 31-43 keratin 20 Homo sapiens 127-131 18628480-0 2008 lenalidomide enhances natural killer cell and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20+ tumor cells. Lenalidomide 0-12 keratin 20 Homo sapiens 126-130