PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34191473-0	2021	eIF2alpha-ATF4 Pathway Activated by a Change in the Calcium Environment Participates in BCP-Mediated Bone Regeneration.	hydroxyapatite-beta tricalcium phosphate	88-91	eukaryotic translation initiation factor 2A	Rattus norvegicus	0-9	
34191473-3	2021	Endoplasmic reticulum stress (ERs) and the subsequent PERK-eIF2alpha-ATF4 pathway can be activated by various factors, including trauma and intracellular calcium changes, and therefore worth exploring as a potential mechanism in BCP-mediated bone repair.	hydroxyapatite-beta tricalcium phosphate	229-232	eukaryotic translation initiation factor 2A	Rattus norvegicus	59-68	
34191473-6	2021	The results showed that the ERs and eIF2alpha-ATF4 pathway activation were observed during 4 weeks of bone repair, with a rapid but brief increase immediately after artificial defect surgery and a re-increase after 4 weeks with the resorption of BCP materials.	hydroxyapatite-beta tricalcium phosphate	246-249	eukaryotic translation initiation factor 2A	Rattus norvegicus	36-45	
34191473-7	2021	Mild ERs and the activated eIF2alpha induced by the calcium changes mediated by BCP regulated the expression of osteogenic-related proteins and had an important role during the defect repair.	hydroxyapatite-beta tricalcium phosphate	80-83	eukaryotic translation initiation factor 2A	Rattus norvegicus	27-36	
34191473-8	2021	In conclusion, the eIF2alpha-ATF4 pathway activated by a change in the calcium environment participates in BCP-mediated bone regeneration.	hydroxyapatite-beta tricalcium phosphate	107-110	eukaryotic translation initiation factor 2A	Rattus norvegicus	19-28