PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29353218-0 2018 Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ss/Fyn pathway. sulforaphane 0-12 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 22-36 29353218-4 2018 METHODS AND RESULTS: Administration of a subpressor dose of Ang II to wild-type mice induced cardiac oxidative stress, inflammation, remodeling and dysfunction, all of which could be prevented by SFN treatment with Nrf2 up-regulation and activation. sulforaphane 196-199 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 60-66 29353218-6 2018 Meanwhile, the ability of SFN to protect against Ang II-induced cardiac damage was lost in Nrf2-KO mice. sulforaphane 26-29 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 49-55 32895018-11 2020 In synhACE2-/- mice, the central Ang II pressor response was attenuated by simultaneous intracerebroventricular infusion of the Nrf2 activator sulforaphane; blood pressure was enhanced by knockdown of Nrf2 in the rostral ventrolateral medulla in Nrf2 floxed (Nrf2f/f) mice. sulforaphane 143-155 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 33-39 28191275-0 2017 Sulforaphane Prevents Angiotensin II-Induced Testicular Cell Death via Activation of NRF2. sulforaphane 0-12 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 22-36 28191275-7 2017 The present study indicated that Ang II may result in testicular apoptotic cell death, which can be prevented by SFN via the activation of NRF2. sulforaphane 113-116 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) Mus musculus 33-39