PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16377050-2 2006 Sulforaphane up-regulates transcription of Phase II detoxification proteins (e.g. quinone reductase [QR]), whereas Se is needed for the production of thioredoxin reductase (TR) and glutathione peroxidase-1 (GPx1), both of which exhibit antioxidant activity. sulforaphane 0-12 crystallin, zeta Mus musculus 82-99 28487960-15 2017 In conclusion, these results suggested that SFN treatment of pulmonary fibrosis mouse models may attenuate alveolitis, fibrosis, apoptosis and lung oxidative stress by increasing the expression of antioxidant enzymes, including NAPDH quinone oxidoreductase, heme oxygenase-1, superoxide dismutase and catalase, via upregulation of Nrf2 gene expression. sulforaphane 44-47 crystallin, zeta Mus musculus 234-256 1549603-9 1992 Sulforaphane and its sulfide and sulfone analogues induced both quinone reductase and glutathione transferase activities in several mouse tissues. sulforaphane 0-12 crystallin, zeta Mus musculus 64-81 16117612-0 2005 Induction of quinone reductase by sulforaphane and sulforaphane N-acetylcysteine conjugate in murine hepatoma cells. sulforaphane 34-46 crystallin, zeta Mus musculus 13-30 16117612-0 2005 Induction of quinone reductase by sulforaphane and sulforaphane N-acetylcysteine conjugate in murine hepatoma cells. sulforaphane 51-63 crystallin, zeta Mus musculus 13-30 9600344-2 1998 4-Methylsulphinylbutyl isothiocyanate (sulphoraphane), derived from the corresponding glucosinolate found in broccoli, has previously been identified as a potent inducer of the anticarcinogenic marker enzyme quinone reductase [NADP(H):quinone-acceptor oxidoreductase] in murine hepatoma Hepa 1c1c7 cells. sulforaphane 39-52 crystallin, zeta Mus musculus 208-225 15184012-9 2004 The induction of QR in cultured mouse hepatoma Hepa lclc7 cells paralleled increases in sulforaphane formation. sulforaphane 88-100 crystallin, zeta Mus musculus 17-19 12416265-3 2002 In this study, we compared the effects of seven daily oral doses of crambene (50 mg/kg rat/day) and sulforaphane (50 mg/kg rat/day) on induction of hepatic quinone reductase activity in Fischer 344 rats. sulforaphane 100-112 crystallin, zeta Mus musculus 156-173 12416265-4 2002 The two treatments produced similar effects, with crambene and sulforaphane producing 1.5- and 1.7-fold induction in hepatic quinone reductase activity, respectively. sulforaphane 63-75 crystallin, zeta Mus musculus 125-142 10226522-5 1999 With cultured Hepa 1c1c7 cells, sulforaphane and 1,2-dithiole-3-thione mediated strong induction of quinone reductase, and genistein and ursolic acid were moderate inducers. sulforaphane 32-44 crystallin, zeta Mus musculus 100-117