PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20600671-6 2010 Nevertheless, sulforaphane reduced the level of lactate dehydrogenase and lipoperoxidation products in cells expressing TDP-43 mutant. sulforaphane 14-26 TAR DNA binding protein Homo sapiens 120-126 20600671-7 2010 However, sulforaphane could upregulate the expression of HO-1 and NAD(P)H/quinone oxidoreductase-1 (NQO-1) in cells transfected with the empty vector and the wild-type TDP-43. sulforaphane 9-21 TAR DNA binding protein Homo sapiens 168-174 20600671-8 2010 Thus, sulforaphane protected cells against mutant TDP-43 independent of Nrf2-antioxidant response element (ARE) pathway. sulforaphane 6-18 TAR DNA binding protein Homo sapiens 50-56 20600671-9 2010 How mutant TDP-43 reduces expression of HO-1 and prevents sulforaphane from activating Nrf2 signaling remains to be investigated. sulforaphane 58-70 TAR DNA binding protein Homo sapiens 11-17