PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28120534-5	2017	Moreover, sulforaphane markedly suppressed the expression of IL-6 and alpha-SMA and inhibited Stat3 and Smad3 signaling pathways in keloid fibroblast KF112 cells.	sulforaphane	10-22	interleukin 6	Homo sapiens	61-65	
28120534-8	2017	Furthermore, sulforaphane suppressed IL-6, Stat3, and Smad3 signaling in the coculture system.	sulforaphane	13-25	interleukin 6	Homo sapiens	37-41	
26522776-8	2015	Transformed resistant cells were sensitive to chemical probe (sulforaphane) through inhibition of IL-6/STAT3/NF-kappaB positive feedback loop whereas parental HER2(+) cells did not respond.	sulforaphane	62-74	interleukin 6	Homo sapiens	98-102	
20233902-0	2010	Sulforaphane inhibits constitutive and interleukin-6-induced activation of signal transducer and activator of transcription 3 in prostate cancer cells.	sulforaphane	0-12	interleukin 6	Homo sapiens	39-52	
18636164-0	2008	Stress-associated hormone, norepinephrine, increases proliferation and IL-6 levels of human pancreatic duct epithelial cells and can be inhibited by the dietary agent, sulforaphane.	sulforaphane	168-180	interleukin 6	Homo sapiens	71-75	
18636164-11	2008	Furthermore, sulforaphane also inhibits norepinephrine-mediated increase of the IL-6 levels but not VEGF levels.	sulforaphane	13-25	interleukin 6	Homo sapiens	80-84	
18636164-12	2008	Our study is the first to demonstrate that stress-associated hormone, norepinephrine, can increase the cell proliferation and IL-6 levels of human pancreatic duct epithelial cells, which can be inhibited by sulforaphane, a chemopreventive agent and a natural compound from the Cruciferous vegetables.	sulforaphane	207-219	interleukin 6	Homo sapiens	126-130	
33590951-10	2021	Pretreatment of MDMs from COPD patients with SFN significantly suppressed Pam3CSK4- or LPS-induced TLR2, TLR4 and MyD88 expression, along with a reduction in the production of IL-6 and TNF-alpha (P < 0.05).	sulforaphane	45-48	interleukin 6	Homo sapiens	176-180	
34308769-8	2021	At the same time, sulforaphane weakened the ability of LPS to induce production of inflammatory cytokines (IL-1beta, IL-6, IL-8 and TNF-alpha) and the pro-apoptotic caspases-3 and -9.	sulforaphane	18-30	interleukin 6	Homo sapiens	117-121	
35216054-6	2022	Furthermore, the anti-inflammatory action of sulforaphane-loaded membrane vesicles was demonstrated, as a decrease in interleukins crucial for the development of inflammation, such as TNF-alpha, IL-1beta and IL-6, was observed.	sulforaphane	45-57	interleukin 6	Homo sapiens	208-212	
34033999-0	2021	Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein.	sulforaphane	0-12	interleukin 6	Homo sapiens	40-53	
34004418-7	2021	RESULTS: In this study, 4 wk of sulforaphane intake decreased plasma levels of creatine kinase, especially creatine kinase levels from 30 min to 24 h and baseline to 24 h. Moreover, the change in interleukin-6 levels significantly decreased from baseline to 30 min on prolonged intake of sulforaphane.	sulforaphane	32-44	interleukin 6	Homo sapiens	196-209	
34004418-7	2021	RESULTS: In this study, 4 wk of sulforaphane intake decreased plasma levels of creatine kinase, especially creatine kinase levels from 30 min to 24 h and baseline to 24 h. Moreover, the change in interleukin-6 levels significantly decreased from baseline to 30 min on prolonged intake of sulforaphane.	sulforaphane	288-300	interleukin 6	Homo sapiens	196-209	
33592002-12	2021	Finally, sulforaphane significantly inhibited the production of IL-6, TNF-alpha, and IL-17 by human peripheral blood mononuclear cells stimulated with an anti-CD3 monoclonal antibody in a dose-dependent manner.	sulforaphane	9-21	interleukin 6	Homo sapiens	64-68	
32041439-10	2020	Sulforaphane significantly inhibited the levels of inflammatory mediators including TSLP, tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, IL-6, and IL-8 in a dose-dependent manner.	sulforaphane	0-12	interleukin 6	Homo sapiens	149-153