PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23624066-1 2013 Sulforaphane; [1-isothiocyanato-4-(methylsulfinyl) butane], (SFN) is an isothiocyanate derived from glucoraphanin present in cruciferous vegetables and has a variety of potential chemopreventive actions. sulforaphane 0-12 RNA exonuclease 2 Homo sapiens 61-64 23624066-1 2013 Sulforaphane; [1-isothiocyanato-4-(methylsulfinyl) butane], (SFN) is an isothiocyanate derived from glucoraphanin present in cruciferous vegetables and has a variety of potential chemopreventive actions. sulforaphane 15-57 RNA exonuclease 2 Homo sapiens 61-64 20233902-1 2010 D,L-sulforaphane (SFN), a synthetic analogue of broccoli-derived L-isomer, inhibits viability of human prostate cancer cells and prevents development of prostate cancer and distant site metastasis in a transgenic mouse model. sulforaphane 0-16 RNA exonuclease 2 Homo sapiens 18-21 23509350-2 2013 In this study, we investigated the effects of ITCs on TLR signaling, and found that the two most promising ITCs, phenethyl ITCs (PEITC) and D,L-sulforaphane (SFN), have differential effects on dsRNA-mediated innate immune signaling through TLR3. sulforaphane 158-161 RNA exonuclease 2 Homo sapiens 140-156 21465338-1 2012 Brassica vegetables are attracting a great deal of attention as healthy foods because of the fact that they contain substantial amounts of secondary metabolite glucosinolates that are converted into isothiocyanates, such as sulforaphane [(-)1-isothiocyanato-4R-(methylsulfinyl)-butane] (R-SFN), through the actions of chopping or chewing the vegetables. sulforaphane 224-236 RNA exonuclease 2 Homo sapiens 289-292 21956685-1 2012 Cancer chemopreventive response to D,L-sulforaphane (SFN), a synthetic racemic analogue of broccoli constituent L-sulforaphane, is partly attributable to apoptosis induction, but the mechanism of cell death is not fully understood. sulforaphane 53-56 RNA exonuclease 2 Homo sapiens 35-51 21116791-1 2010 Sulforaphane (4-methylsulfinylbutyl isothiocyanate, SFN) from broccoli has been used a chemopreventive photochemical as detoxification of xenobiotics and anti-inflammatory, however, there is no studies for Th2 chemokine expression through heme oxygenase-1 and NF-kappaB in keratinocytes. sulforaphane 0-12 RNA exonuclease 2 Homo sapiens 52-55 33966346-4 2021 Sulforaphane-N-acetylcysteine (SFN-N-acetylcysteine or SFN-NAC), a sulforaphane metabolite has shown significantly superior activity against HDACs under in vitro conditions. sulforaphane 67-79 RNA exonuclease 2 Homo sapiens 31-34 17513615-1 2007 Previous studies have indicated that d,l-sulforaphane (SFN), a synthetic cancer chemopreventive analogue of cruciferous vegetable-derived isomer (-)-1-isothiocyanato-(4R)-(methylsulfinyl)-butane, activates a checkpoint kinase 2 (Chk2)-dependent G(2)-M phase cell cycle arrest in p53-deficient human prostate cancer cells. sulforaphane 37-53 RNA exonuclease 2 Homo sapiens 55-58 33774519-1 2021 Sulforaphane(SFN) and erucin(ERN) are isothiocyanates (ITCs) bearing, respectively, methylsulfinyl and methylsulfanyl groups. sulforaphane 0-12 RNA exonuclease 2 Homo sapiens 13-16 33966346-4 2021 Sulforaphane-N-acetylcysteine (SFN-N-acetylcysteine or SFN-NAC), a sulforaphane metabolite has shown significantly superior activity against HDACs under in vitro conditions. sulforaphane 67-79 RNA exonuclease 2 Homo sapiens 55-58 33448841-2 2019 Therefore, we have built a multifunctional nanosystem based on sulforaphane-conjugated carbon dots (SFN-CDs) with thiourea skeleton and applied for EGFR-overexpressing cancer cells targeted imaging and inhibiting. sulforaphane 63-75 RNA exonuclease 2 Homo sapiens 100-103 32659677-2 2020 Sulforaphane (4-methylsulfinylbutyl isothiocyanate, SFN), commonly found in cruciferous vegetables, has diverse biological effects on skin tissue. sulforaphane 0-12 RNA exonuclease 2 Homo sapiens 52-55 33448841-3 2019 The SFN-CDs are formed by grafting sulforaphane on the amino-rich yellow fluorescent carbon dots, which have excellent optical stability and can be distinguished from normal cells for targeted imaging of cancer cells. sulforaphane 35-47 RNA exonuclease 2 Homo sapiens 4-7 29924910-2 2018 The ITC l-sulforaphane (l-SFN) is the principle agent in broccoli that demonstrates several modes of anticancer action. sulforaphane 8-22 RNA exonuclease 2 Homo sapiens 26-29 27218607-3 2016 The goal was to investigate the putative effects of natural antioxidant sulforaphane (1-isothiocyanate-4-methyl-sulfonyl butane; SFN) on browning of white adipocytes. sulforaphane 72-84 RNA exonuclease 2 Homo sapiens 129-132 27261601-8 2016 This review deals with plant derived HDACi sulphoraphane (SFN; 1-isothiocyanato-4-(methylsulfinyl)-butane) and its potential role in prostate cancer therapy along with the underlying molecular mechanism being involved. sulforaphane 43-56 RNA exonuclease 2 Homo sapiens 58-61 27261601-8 2016 This review deals with plant derived HDACi sulphoraphane (SFN; 1-isothiocyanato-4-(methylsulfinyl)-butane) and its potential role in prostate cancer therapy along with the underlying molecular mechanism being involved. sulforaphane 63-105 RNA exonuclease 2 Homo sapiens 58-61 24092501-1 2014 PURPOSE: D,L-Sulforaphane (SFN) is a promising chemopreventive agent with in vivo efficacy against prostate cancer in experimental rodents. sulforaphane 9-25 RNA exonuclease 2 Homo sapiens 27-30