PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27228663-1 2016 By means of spectrophotometric assay we investigated interaction of the dye Congo red (CR) with fibrils of model proteins--hen egg white lysozyme, recombinant human beta2-microglobulin (b2M) and recombinant human transthyretin (TTR). Congo Red 76-85 beta-2-microglobulin Homo sapiens 165-184 27228663-1 2016 By means of spectrophotometric assay we investigated interaction of the dye Congo red (CR) with fibrils of model proteins--hen egg white lysozyme, recombinant human beta2-microglobulin (b2M) and recombinant human transthyretin (TTR). Congo Red 87-89 beta-2-microglobulin Homo sapiens 165-184 20396423-4 2010 Biopsy of one of these nodules revealed beta2-microglobulin amyloidosis by histopathology, Congo red stain, electron microscopy, and immunohistochemistry. Congo Red 91-100 beta-2-microglobulin Homo sapiens 40-59 18383026-7 2008 An increased unfolding, aggregation, and induction of Congo red-reactive molecular species in Cu(2+)-incubated wt-beta(2)m could be demonstrated while the refolding kinetics of dK58-beta(2)m, already slower than the wt molecule, appeared not to be further decreased by Cu(2+). Congo Red 54-63 beta-2-microglobulin Homo sapiens 114-122 11801591-7 2002 In the cleaved and trimmed beta(2)-microglobulin that appears in vivo, the less populated conformation is characterized by an increased affinity for Congo red. Congo Red 149-158 beta-2-microglobulin Homo sapiens 27-48 15766269-5 2005 The unfolding rate is 1 order of magnitude faster in DeltaK58-beta(2)m than in wt-beta(2)m, and at 37 degrees C the half-time for unfolding is more than 170-fold faster than at 15 degrees C. Conformational changes are also reflected by a very prominent Congo red binding of DeltaK58-beta(2)m at 37 degrees C, by the evolution of thioflavin T fluorescence, and by changes in intrinsic fluorescence. Congo Red 253-262 beta-2-microglobulin Homo sapiens 62-70 15766269-5 2005 The unfolding rate is 1 order of magnitude faster in DeltaK58-beta(2)m than in wt-beta(2)m, and at 37 degrees C the half-time for unfolding is more than 170-fold faster than at 15 degrees C. Conformational changes are also reflected by a very prominent Congo red binding of DeltaK58-beta(2)m at 37 degrees C, by the evolution of thioflavin T fluorescence, and by changes in intrinsic fluorescence. Congo Red 253-262 beta-2-microglobulin Homo sapiens 82-90 15766269-5 2005 The unfolding rate is 1 order of magnitude faster in DeltaK58-beta(2)m than in wt-beta(2)m, and at 37 degrees C the half-time for unfolding is more than 170-fold faster than at 15 degrees C. Conformational changes are also reflected by a very prominent Congo red binding of DeltaK58-beta(2)m at 37 degrees C, by the evolution of thioflavin T fluorescence, and by changes in intrinsic fluorescence. Congo Red 253-262 beta-2-microglobulin Homo sapiens 82-90 11100875-2 2000 CE could separate conformational variants of beta2-microglobulin and with the amyloid-specific dye Congo red as a buffer additive it was possible to measure different Congo red-affinities of native and abnormally folded beta2-microglobulin. Congo Red 99-108 beta-2-microglobulin Homo sapiens 220-239 11418618-8 2001 Affinity capillary electrophoresis experiments showed increased specific interactions of the nonnative beta(2)-microglobulin conformation with the dyes 8-anilino-1-naphthalene sulfonic acid and Congo red. Congo Red 194-203 beta-2-microglobulin Homo sapiens 103-124 11100875-0 2000 Congophilicity (Congo red affinity) of different beta2-microglobulin conformations characterized by dye affinity capillary electrophoresis. Congo Red 16-25 beta-2-microglobulin Homo sapiens 49-68 11100875-2 2000 CE could separate conformational variants of beta2-microglobulin and with the amyloid-specific dye Congo red as a buffer additive it was possible to measure different Congo red-affinities of native and abnormally folded beta2-microglobulin. Congo Red 167-176 beta-2-microglobulin Homo sapiens 220-239 11100875-3 2000 We find that native beta2-microglobulin has an intermediate affinity for Congo red at pH 7.3 and that binding involves electrostatic interactions. Congo Red 73-82 beta-2-microglobulin Homo sapiens 20-39 11100875-4 2000 The conformational variant of beta2-microglobulin that appears in acetonitrile solutions binds Congo red more strongly. Congo Red 95-104 beta-2-microglobulin Homo sapiens 30-49 10913285-2 2000 Using Congo red and thioflavin-T binding, electron microscopy, and X-ray fiber diffraction, we have determined conditions under which recombinant monomeric beta(2)m spontaneously associates to form fibrils in vitro. Congo Red 6-15 beta-2-microglobulin Homo sapiens 156-164 1280700-8 1992 Among them, only the reaction of anti-amyloid P component had significantly distinctive localization to A beta 2M deposits, which were identified in adjacent serial sections by Congo red staining and immunohistochemical reaction against anti-beta 2m. Congo Red 177-186 beta-2-microglobulin Homo sapiens 106-113 7653483-8 1995 Beta 2-microglobulin amyloid was identified by Congo red staining and immunohistology. Congo Red 47-56 beta-2-microglobulin Homo sapiens 0-20 1729018-3 1992 The plasma level of beta 2-microglobulin in this patient was elevated, and bone specimens from the fracture site demonstrated positive Congo-red staining, suggesting an association with amyloid deposition. Congo Red 135-144 beta-2-microglobulin Homo sapiens 20-40 2178825-4 1990 Nine of the patients proved to have beta 2-microglobulin amyloid deposits as demonstrated by Congo red staining and by immunofluorescence. Congo Red 93-102 beta-2-microglobulin Homo sapiens 36-56