PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24394665-0 2014 Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34(+) cells. Bortezomib 0-10 lymphoid enhancer binding factor 1 Homo sapiens 51-56 24394665-8 2014 The proteasome inhibitor bortezomib reversed the defective G-CSF-triggered granulocytic differentiation of CD34(+) cells from CN patients in vitro, an effect that was accompanied by restoration of LEF-1 protein levels and LEF-1 messenger RNA autoregulation. Bortezomib 25-35 lymphoid enhancer binding factor 1 Homo sapiens 197-202 24394665-8 2014 The proteasome inhibitor bortezomib reversed the defective G-CSF-triggered granulocytic differentiation of CD34(+) cells from CN patients in vitro, an effect that was accompanied by restoration of LEF-1 protein levels and LEF-1 messenger RNA autoregulation. Bortezomib 25-35 lymphoid enhancer binding factor 1 Homo sapiens 222-227