PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29069787-8 2017 Here, we demonstrate that carfilzomib and bortezomib stabilize the HER2-specific protein tyrosine phosphatase BDP1 leading to decreased HER2 autophosphorylation, reduced HER2 activity and subsequently attenuated activation of the PI3K/Akt-pathway, together with blockade of ERalpha expression. Bortezomib 42-52 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB Homo sapiens 110-114