PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24943733-10 2014 Piroxicam, used as reference drug, significantly reduced the levels of COX-1, COX-2, PGE2, NF-kB, and TNF-alpha, but did not show reduction in 5-LOX and toll-like receptor 2 levels. Piroxicam 0-9 tumor necrosis factor Rattus norvegicus 102-111 12180128-5 2002 Both oxicams produced a similar extent of the gastric mucosal damage and a significant decrease in PGE2 synthesis, however only piroxicam induced an increase of both myeloperoxidase (MPO) activity and tumor necrosis factor (TNF)-alpha content in the gastric mucosa, indicating that neutrophil-derived free radicals were involved in gastric injury. Piroxicam 128-137 tumor necrosis factor Rattus norvegicus 201-234