PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19379215-3	2005	A phase II clinical trial of carboplatin combined with the cox inhibitor, piroxicam, was performed in 31 dogs with naturally occurring, histopathologically confirmed, measurable TCC.	Piroxicam	74-83	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	59-62	
19379215-10	2005	In conclusion, carboplatin/piroxicam induced remission in 40% of dogs providing evidence that a cox inhibitor enhances the antitumour activity of carboplatin.	Piroxicam	27-36	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	96-99	
12589035-0	2003	Effects of the cyclooxygenase inhibitor, piroxicam, in combination with chemotherapy on tumor response, apoptosis, and angiogenesis in a canine model of human invasive urinary bladder cancer.	Piroxicam	41-50	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	15-29	
15198222-6	2004	RESULTS: Aspirin, diclofenac, indomethacin, ketoprofen, meclofenamic acid, and piroxicam had little selectivity toward COX isozymes, whereas NS398, carprofen, tolfenamic acid, nimesulide, and etodolac had more than 5 times greater preference for inhibiting COX-2 than COX-1.	Piroxicam	79-88	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	119-122	
12589035-1	2003	The objectives of this study were: (a) to determine the antitumor activity and toxicity of a cyclooxygenase inhibitor (piroxicam) combined with cisplatin chemotherapy in dogs with naturally-occurring, invasive transitional cell carcinoma (TCC) of the urinary bladder; and (b) to determine the effects of this treatment on prostaglandin E(2) concentration, tumor cell proliferation and apoptosis, and angiogenesis.	Piroxicam	119-128	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	93-107	
11809678-0	2002	Effects of the cyclooxygenase inhibitor, piroxicam, on tumor response, apoptosis, and angiogenesis in a canine model of human invasive urinary bladder cancer.	Piroxicam	41-50	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	15-29	
11021739-3	2000	The purpose of this study was to determine whether cisplatin combined with the cox-inhibitor piroxicam would induce remission more frequently than cisplatin alone in a relevant animal model of human invasive TCC.	Piroxicam	93-102	prostaglandin-endoperoxide synthase 1	Canis lupus familiaris	79-82