PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9008610-9 1997 Interestingly, piroxicam prevented the conformational changes that beta 2 integrins underwent upon activation of neutrophils: the appearance of the activation epitope of CD11b, detected by the CBRM1/5 MAb, was blocked by piroxicam in TNF alpha-treated neutrophils. Piroxicam 15-24 integrin subunit alpha M Homo sapiens 170-175 9008610-9 1997 Interestingly, piroxicam prevented the conformational changes that beta 2 integrins underwent upon activation of neutrophils: the appearance of the activation epitope of CD11b, detected by the CBRM1/5 MAb, was blocked by piroxicam in TNF alpha-treated neutrophils. Piroxicam 221-230 integrin subunit alpha M Homo sapiens 170-175 9067636-4 1997 Addition of the cyclooxygenase inhibitors indomethacin (10 microM) or piroxicam (20 microM) slightly increased expression of CD11b and CD18 in cells differentiated with RA, but did not alter expression of surface antigens in cells treated with 1,25-D3. Piroxicam 70-79 integrin subunit alpha M Homo sapiens 125-130 2138999-6 1990 Both piroxicam and indomethacin inhibited FMLP-induced upregulation of CD11b, CD11c, and CD35, but neither drug affected the upregulation of these surface molecules induced by C5a or ionomycin. Piroxicam 5-14 integrin subunit alpha M Homo sapiens 71-76 2138999-9 1990 We conclude that piroxicam and indomethacin inhibit FMLP receptor-mediated upregulation of CD11b, CD11c, and CD35 in PMNs, but have no effect on the upregulation of these molecules by ionomycin or C5a. Piroxicam 17-26 integrin subunit alpha M Homo sapiens 91-96