PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23002242-2	2013	This study was designed to evaluate the reciprocal regulation of KLF2 by the forkhead transcription factor FOXO1, and the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor atorvastatin, in hyperglycaemic conditions.	Atorvastatin	180-192	Kruppel-like factor 2	Rattus norvegicus	65-69	
23002242-6	2013	Interestingly, atorvastatin inhibited FOXO1 by increasing phosphorylation and also by inhibiting nuclear localization and replenished KLF2 in high-glucose conditions.	Atorvastatin	15-27	Kruppel-like factor 2	Rattus norvegicus	134-138	
23002242-8	2013	Chromatin immunoprecipitation analysis demonstrated that glucose increased whereas atorvastatin decreased FOXO1 binding to the promoter region of the KLF2 gene.	Atorvastatin	83-95	Kruppel-like factor 2	Rattus norvegicus	150-154	
23002242-9	2013	In the vessels of Otsuka Long-Evans Tokushima Fatty rats, animal models of type 2 diabetes, FOXO1 was activated and KLF2 was suppressed, and this was reversed by atorvastatin treatment.	Atorvastatin	162-174	Kruppel-like factor 2	Rattus norvegicus	116-120	
23002242-12	2013	High-glucose-induced, FOXO1-mediated KLF2 suppression was reversed by atorvastatin, suggesting that intensive statin treatment could be a therapeutic option in diabetic vascular dysfunction.	Atorvastatin	70-82	Kruppel-like factor 2	Rattus norvegicus	37-41