PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32111984-6 2020 In addition, SOX13 was shown to be a direct target of HGF/STAT3 signaling, and the c-MET inhibitor crizotinib blocked the HGF/STAT3/SOX13/c-MET axis, significantly inhibiting SOX13-mediated CRC migration, invasion and metastasis. Crizotinib 99-109 SRY-box transcription factor 13 Homo sapiens 132-137 32111984-6 2020 In addition, SOX13 was shown to be a direct target of HGF/STAT3 signaling, and the c-MET inhibitor crizotinib blocked the HGF/STAT3/SOX13/c-MET axis, significantly inhibiting SOX13-mediated CRC migration, invasion and metastasis. Crizotinib 99-109 SRY-box transcription factor 13 Homo sapiens 132-137 32111984-9 2020 In summary, SOX13 is a promising prognostic biomarker in patients with CRC, and blocking the HGF/STAT3/SOX13/c-MET axis with crizotinib could be a new therapeutic strategy to prevent SOX13-mediated CRC metastasis. Crizotinib 125-135 SRY-box transcription factor 13 Homo sapiens 103-108 32111984-9 2020 In summary, SOX13 is a promising prognostic biomarker in patients with CRC, and blocking the HGF/STAT3/SOX13/c-MET axis with crizotinib could be a new therapeutic strategy to prevent SOX13-mediated CRC metastasis. Crizotinib 125-135 SRY-box transcription factor 13 Homo sapiens 103-108