PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25481395-3 2015 The configuration of 19 was determined by (1)H NMR and NOESY spectra as syn-isomers, suggesting that the cycloaddition of topotecan with alkyl vinyl ethers could undergo a hetero Diels-Alder reaction. Topotecan 122-131 synemin Homo sapiens 72-75