PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22053213-7 2011 Epidermal growth factor receptor (EGFR) signaling pathways contribute to the biological aggressiveness of PDAC, and we found that the motogenic effects of DeltaNp63alpha were augmented in presence of EGF. pdac 106-110 epidermal growth factor receptor Homo sapiens 0-32 27435925-2 2016 Our previous study suggested that epidermal growth factor receptor inhibitor erlotinib which acts upstream of these pathways acts synergistically with PI3K inhibitors in PDAC. pdac 170-174 epidermal growth factor receptor Homo sapiens 34-66 24625091-9 2014 In contrast, SMAD4 loss in PDAC leads to increased expression of E-cadherin, vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR) and CD133. pdac 27-31 epidermal growth factor receptor Homo sapiens 120-152 24625091-9 2014 In contrast, SMAD4 loss in PDAC leads to increased expression of E-cadherin, vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR) and CD133. pdac 27-31 epidermal growth factor receptor Homo sapiens 154-158 27391842-5 2016 RESULTS: Among the lesions of PDAC, 12 (13 %) stained positive for EGFRvIII, 49 (53.3 %) stained positive for AREG and 22(23.9 %) stained double positive for AREG/EGFR. pdac 30-34 epidermal growth factor receptor Homo sapiens 67-71 24895459-2 2014 The hypothesis of this study is that PI3K and EGFR coinhibition may be effective in PDAC with upregulated PI3K-Akt signaling. pdac 84-88 epidermal growth factor receptor Homo sapiens 46-50 24895459-12 2014 CONCLUSION: PDAC with increased expression of the PI3K-Akt pathway was susceptible to PI3K-EGFR coinhibition, suggesting oncogenic dependence. pdac 12-16 epidermal growth factor receptor Homo sapiens 91-95 24520077-5 2014 Exposure of colorectal cancer and PDAC cells to DCA resulted in colocalization of Src and TACE to the cell membrane, resulting in AREG-dependent activation of EGFR, mitogen-activated protein kinase (MAPK), and STAT3 signaling. pdac 34-38 epidermal growth factor receptor Homo sapiens 159-163 22053213-7 2011 Epidermal growth factor receptor (EGFR) signaling pathways contribute to the biological aggressiveness of PDAC, and we found that the motogenic effects of DeltaNp63alpha were augmented in presence of EGF. pdac 106-110 epidermal growth factor receptor Homo sapiens 34-38