PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27386488-3 2016 Our previous studies revealed that PDX1 promotes tumorigenesis and it is a promising therapeutic target for PDAC. pdac 108-112 pancreatic and duodenal homeobox 1 Homo sapiens 35-39 24713432-3 2014 More specifically, impaired JNK signaling in a subpopulation of Pdx1-expressing cells dramatically accelerated the appearance of Kras(G12D)-induced acinar-to-ductal metaplasia and pancreatic intraepithelial neoplasias, which rapidly progressed to invasive PDAC within 10 weeks of age. pdac 256-260 pancreatic and duodenal homeobox 1 Homo sapiens 64-68 23719586-5 2013 CONCLUSIONS: This work indicates that expression of KRAS(G12D) in Pdx1-expressing cells during embryogenesis affects the endocrine pancreas, and highlights the need to deepen possible consequences on both glucose metabolism and PDAC initiation. pdac 228-232 pancreatic and duodenal homeobox 1 Homo sapiens 66-70