PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28217977-0	2017	miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression.	Oxaliplatin	69-80	microRNA 506	Homo sapiens	0-7	
28217977-2	2017	The aim of this study was to elucidate the mechanism by which miR-506 reverses oxaliplatin chemoresistance in CRC.	Oxaliplatin	79-90	microRNA 506	Homo sapiens	62-69	
28217977-12	2017	miR-506 overexpression inhibited cell growth and increased oxaliplatin-induced cell apoptosis in HCT116-OxR cells, as shown via FCM and apoptosis assay.	Oxaliplatin	59-70	microRNA 506	Homo sapiens	0-7	
28217977-15	2017	CONCLUSION: Taken together, the findings of our study demonstrate that miR-506 overexpression in HCT116-OxR cells enhances oxaliplatin sensitivity by inhibiting MDR1/P-gp expression via down-regulation of the Wnt/beta-catenin pathway and thus provide a rationale for the development of miRNA-based strategies to reverse oxaliplatin resistance in CRC cells.	Oxaliplatin	123-134	microRNA 506	Homo sapiens	71-78	
28217977-15	2017	CONCLUSION: Taken together, the findings of our study demonstrate that miR-506 overexpression in HCT116-OxR cells enhances oxaliplatin sensitivity by inhibiting MDR1/P-gp expression via down-regulation of the Wnt/beta-catenin pathway and thus provide a rationale for the development of miRNA-based strategies to reverse oxaliplatin resistance in CRC cells.	Oxaliplatin	320-331	microRNA 506	Homo sapiens	71-78