PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22766915-6	2012	Downregulation of TS and DPD expression and upregulation of OPRT expression were induced by DOC treatment, suggesting that DOC enhanced the efficacy of 5-FU by altering the expression of its metabolic enzymes.	Docetaxel	92-95	uridine monophosphate synthetase	Homo sapiens	60-64	
22766915-6	2012	Downregulation of TS and DPD expression and upregulation of OPRT expression were induced by DOC treatment, suggesting that DOC enhanced the efficacy of 5-FU by altering the expression of its metabolic enzymes.	Docetaxel	123-126	uridine monophosphate synthetase	Homo sapiens	60-64	
16897978-12	2006	The expressions of thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) were decreased and that of orotate phosphorybosyl transferase (OPRT) was increased in mRNA, protein level and activity assay after the treatment with docetaxel and 5-FU in the TMK-1 gastric cancer cell.	Docetaxel	237-246	uridine monophosphate synthetase	Homo sapiens	114-148	
16897978-12	2006	The expressions of thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) were decreased and that of orotate phosphorybosyl transferase (OPRT) was increased in mRNA, protein level and activity assay after the treatment with docetaxel and 5-FU in the TMK-1 gastric cancer cell.	Docetaxel	237-246	uridine monophosphate synthetase	Homo sapiens	150-154