PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34184786-6 2021 Moreover, knocking down GAS5 protects C4-2 cells from the docetaxel-induced cell apoptosis. Docetaxel 58-67 growth arrest specific 5 Homo sapiens 24-28 34094978-0 2021 A Long Noncoding RNA, GAS5 Can Be a Biomarker for Docetaxel Response in Castration Resistant Prostate Cancer. Docetaxel 50-59 growth arrest specific 5 Homo sapiens 22-26 34094978-2 2021 Here, we test the hypothesis that the expression of a lncRNA, grow arrest-specific 5 (GAS5) can be a biomarker for docetaxel response in castration resistant prostate cancer (CRPC) using both prostate cancer (PCa) cell lines and CRPC patient datasets. Docetaxel 115-124 growth arrest specific 5 Homo sapiens 62-84 34094978-2 2021 Here, we test the hypothesis that the expression of a lncRNA, grow arrest-specific 5 (GAS5) can be a biomarker for docetaxel response in castration resistant prostate cancer (CRPC) using both prostate cancer (PCa) cell lines and CRPC patient datasets. Docetaxel 115-124 growth arrest specific 5 Homo sapiens 86-90 34094978-3 2021 Our results suggest that lower GAS5 expression is associated with docetaxel resistance in both PCa cell lines and CRPC patients. Docetaxel 66-75 growth arrest specific 5 Homo sapiens 31-35 34094978-4 2021 Further experiments also suggest that GAS5 is downregulated in docetaxel resistant CRPC cell lines, which reinforces its potential as a biomarker for docetaxel response. Docetaxel 63-72 growth arrest specific 5 Homo sapiens 38-42 34094978-4 2021 Further experiments also suggest that GAS5 is downregulated in docetaxel resistant CRPC cell lines, which reinforces its potential as a biomarker for docetaxel response. Docetaxel 150-159 growth arrest specific 5 Homo sapiens 38-42 34094978-11 2021 In conclusion, our work suggests that GAS5 can serve as a predictive biomarker for docetaxel response in CRPC; however, the exact mechanism behind the observed correlation remain to be elucidated. Docetaxel 83-92 growth arrest specific 5 Homo sapiens 38-42