PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32920545-5 2020 Mechanism dissection found that Doc treatment might increase the generation of ARv7 via altering the MALAT1-SF2 RNA splicing complex. Docetaxel 32-35 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 101-107 30771618-0 2019 TFAP2C-Activated MALAT1 Modulates the Chemoresistance of Docetaxel-Resistant Lung Adenocarcinoma Cells. Docetaxel 57-66 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 17-23 30771618-5 2019 Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) contributed to the low miR-200b level in DTX-resistant LUAD cells. Docetaxel 105-108 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 0-54 30771618-5 2019 Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) contributed to the low miR-200b level in DTX-resistant LUAD cells. Docetaxel 105-108 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 56-62 30771618-6 2019 Functional assays were conducted to determine the role of MALAT1 in regulating the growth and metastasis of parental and DTX-resistant LUAD cells. Docetaxel 121-124 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 58-64 30771618-9 2019 MALAT1 modulated the sensitivity of LUAD cells to DTX. Docetaxel 50-53 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 0-6 30771618-10 2019 E2F transcription factor 3 (E2F3) and zinc-finger E-box binding homeobox 1 (ZEB1) were two targets of miR-200b and mediated the function of MALAT1 in DTX-resistant LUAD cells. Docetaxel 150-153 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 140-146 29633510-0 2018 Long noncoding RNA MALAT1 enhances the docetaxel resistance of prostate cancer cells via miR-145-5p-mediated regulation of AKAP12. Docetaxel 39-48 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 19-25 29633510-9 2018 Tumour xenograft study was undertaken to confirm the correlation of MALAT1/miR-145-5p/AKAP12 axis and DTX sensitivity of PCa cells in vivo. Docetaxel 102-105 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 68-74 29633510-10 2018 In this study, we firstly notified that the MALAT1 expression levels were up-regulated in clinical DTX-resistant PCa samples. Docetaxel 99-102 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 44-50 29633510-11 2018 Overexpressed MALAT1 promoted cell proliferation, migration and invasion but decreased cell apoptosis rate of PCa cells in spite of DTX treatment. Docetaxel 132-135 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 14-20 29633510-13 2018 MiR-145-5p overexpression in PC3-DTX led to inhibited cell proliferation, migration and invasion as well as reduced chemoresistance to DTX, which was attenuated by MALAT1. Docetaxel 33-36 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 164-170 29633510-15 2018 Besides, it was proved that MALAT1 promoted tumour cell proliferation and enhanced DTX-chemoresistance in vivo. Docetaxel 83-86 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 28-34 29633510-16 2018 There was an lncRNA MALAT1/miR-145-5p/AKAP12 axis involved in DTX resistance of PCa cells and provided a new thought for PCa therapy. Docetaxel 62-65 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 20-26 29633510-1 2018 Our present work was aimed to study on the regulatory role of MALAT1/miR-145-5p/AKAP12 axis on docetaxel (DTX) sensitivity of prostate cancer (PCa) cells. Docetaxel 95-104 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 62-68 29633510-1 2018 Our present work was aimed to study on the regulatory role of MALAT1/miR-145-5p/AKAP12 axis on docetaxel (DTX) sensitivity of prostate cancer (PCa) cells. Docetaxel 106-109 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 62-68 29633510-3 2018 QRT-PCR analysis was performed to measure MALAT1 expression in DTX-sensitive and DTX-resistant tissues/cells. Docetaxel 63-66 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 42-48 29633510-3 2018 QRT-PCR analysis was performed to measure MALAT1 expression in DTX-sensitive and DTX-resistant tissues/cells. Docetaxel 81-84 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 42-48 29633510-4 2018 The human DTX-resistant cell lines DU145-PTX and PC3-DTX were established as in vitro cell models, and the expression of MALAT1, miR-145-5p and AKAP12 was manipulated in DTX-sensitive and DTX-resistant cells. Docetaxel 10-13 metastasis associated lung adenocarcinoma transcript 1 Homo sapiens 121-127