PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33428605-9 2021 The pro-tumorigenic effects of TAMs or TAM-CM were abolished by TGF-beta signaling pathway inhibitors and neutralizing TGF-beta antibody. tams 31-35 transforming growth factor alpha Homo sapiens 64-72 33428605-9 2021 The pro-tumorigenic effects of TAMs or TAM-CM were abolished by TGF-beta signaling pathway inhibitors and neutralizing TGF-beta antibody. tams 31-35 transforming growth factor alpha Homo sapiens 119-127 33428605-10 2021 These results demonstrate that TAMs promote PDAC progression through the TGF-beta signaling pathway. tams 31-35 transforming growth factor alpha Homo sapiens 73-81 31182919-14 2019 What"s more, M2-polarized TAMs secreted TGF-beta to facilitate the EMT, growth, proliferation and invasion of CRC cells by in vivo and in vitro experiments. tams 26-30 transforming growth factor alpha Homo sapiens 40-48 31182919-15 2019 Conclusions: Our studies preliminarily elucidated the prognostic value of CD163+/CD68+ ratio in different tumor locations and the biological functions of M2-polarized TAMs in CRC progression via TGF-beta. tams 167-171 transforming growth factor alpha Homo sapiens 195-203 34375482-4 2021 In mechanism, TAMs produced the cytokine TGF-beta to support HIF1alpha expression, thereby up-regulating Tribbles Pseudokinase 3 (TRIB3) in tumor cells. tams 14-18 transforming growth factor alpha Homo sapiens 41-49 34207286-7 2021 In fact, clinical evidence has verified that TAMs, representing up to 50% of the tumor mass, exert both protumor and immunosuppressive effects in promoting tumor metastasis through secretion of interleukin 10 (IL10), transforming growth factor beta (TGFbeta), and VEGF, expression of PD-1 and consumption of arginine to inhibit T cell anti-tumor function. tams 45-49 transforming growth factor alpha Homo sapiens 250-257