PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34482462-6	2022	The results showed that nanocurcumin significantly attenuated the lipid peroxidation (MDA), oxidized glutathione, the release of pro-inflammatory cytokines (TNF-alpha and IL-1beta), and the gene expression of TLR4, NF-kappaB p65, and HMGB1.	nanocurcumin	24-36	tumor necrosis factor	Rattus norvegicus	157-166	
25747863-13	2015	Besides, nanocurcumin decreased CSF levels of TNF-alpha and IL-1beta, which may contribute to the extrinsic antiapoptotic effect.	nanocurcumin	9-21	tumor necrosis factor	Rattus norvegicus	46-55	
33404738-0	2021	Chronic nanocurcumin treatment ameliorates pain-related behavior, improves spatial memory, and reduces hippocampal levels of IL-1beta and TNFalpha in the chronic constriction injury model of neuropathic pain.	nanocurcumin	8-20	tumor necrosis factor	Rattus norvegicus	138-146	
33404738-9	2021	Chronic treatment with nanocurcumin significantly increased pain threshold (P < 0.001; F = 27.63, F = 20.58), improved spatial memory (P < 0.01; F = 47.37), and decreased the hippocampal levels of IL-1beta (P < 0.001; F = 33.57) and TNF-alpha (P < 0.01; F = 7.25) in CCI rats.	nanocurcumin	23-35	tumor necrosis factor	Rattus norvegicus	233-242	
33404738-10	2021	CONCLUSION: Chronic nanocurcumin can ameliorate pain-related behavior, improve spatial learning and memory deficits, and is associated with the reduction of IL-1beta and TNF-alpha levels in the hippocampus in CCI rats.	nanocurcumin	20-32	tumor necrosis factor	Rattus norvegicus	170-179	
32589998-0	2020	Nanocurcumin alleviates insulin resistance and pancreatic deficits in polycystic ovary syndrome rats: Insights on PI3K/AkT/mTOR and TNF-alpha modulations.	nanocurcumin	0-12	tumor necrosis factor	Rattus norvegicus	132-141	
32589998-13	2020	Nanocurcumin significantly improved oxidative markers, glucose indices and TNF-alpha levels.	nanocurcumin	0-12	tumor necrosis factor	Rattus norvegicus	75-84