PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31248045-3	2019	We hypothesized that a disruption of pro-survival signaling cascades with the multi-tyrosine kinase inhibitor sunitinib and would be an effective strategy to enhance TRAIL-mediated apoptosis.	Sunitinib	110-119	TNF superfamily member 10	Homo sapiens	166-171	
31248045-4	2019	Here we demonstrate that sunitinib significantly augments the anticancer activity of TRAIL in models of colon cancer.	Sunitinib	25-34	TNF superfamily member 10	Homo sapiens	85-90	
31248045-6	2019	Overexpression of the anti-apoptotic factor B-cell lymphoma 2 (BCL-2) in HCT116 cells reduced TRAIL/sunitinib-mediated apoptosis, further supporting that sunitinib enhances the anticancer activity of TRAIL via augmented apoptosis.	Sunitinib	154-163	TNF superfamily member 10	Homo sapiens	94-99	
31248045-6	2019	Overexpression of the anti-apoptotic factor B-cell lymphoma 2 (BCL-2) in HCT116 cells reduced TRAIL/sunitinib-mediated apoptosis, further supporting that sunitinib enhances the anticancer activity of TRAIL via augmented apoptosis.	Sunitinib	154-163	TNF superfamily member 10	Homo sapiens	200-205	
31248045-10	2019	Collectively, our data demonstrate that sunitinib enhances TRAIL-mediated apoptosis by heightened JNK activation, diminished XIAP levels, and augmented apoptosis.	Sunitinib	40-49	TNF superfamily member 10	Homo sapiens	59-64	
27016208-7	2016	We found that sunitinib enhances TRAIL-induced G0/G1-phase cell cycle arrest and blocks TRAIL-triggered activation of AKT as the underlying mechanism.	Sunitinib	14-23	TNF superfamily member 10	Homo sapiens	33-38	
27016208-7	2016	We found that sunitinib enhances TRAIL-induced G0/G1-phase cell cycle arrest and blocks TRAIL-triggered activation of AKT as the underlying mechanism.	Sunitinib	14-23	TNF superfamily member 10	Homo sapiens	88-93	
27016208-8	2016	In contrast, we observed antagonistic effects when sunitinib was administered after TRAIL to the cell lines tested.	Sunitinib	51-60	TNF superfamily member 10	Homo sapiens	84-89	
20137855-1	2010	The present data showed that sunitinib potentiated the in vitro and in vivo anticancer capabilities of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), also known as Apo2 ligand.	Sunitinib	29-38	TNF superfamily member 10	Homo sapiens	103-158	
20137855-1	2010	The present data showed that sunitinib potentiated the in vitro and in vivo anticancer capabilities of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), also known as Apo2 ligand.	Sunitinib	29-38	TNF superfamily member 10	Homo sapiens	160-165	
20137855-1	2010	The present data showed that sunitinib potentiated the in vitro and in vivo anticancer capabilities of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), also known as Apo2 ligand.	Sunitinib	29-38	TNF superfamily member 10	Homo sapiens	182-193