PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27495788-1	2016	PURPOSE: Pharmacokinetic interaction of sunitinib with diclofenac, paracetamol, mefenamic acid and ibuprofen was evaluated due to their P450 mediated metabolism and OATP1B1, OATP1B3, ABCB1, ABCG2 transporters overlapping features.	Sunitinib	40-49	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	183-188	
22238213-0	2012	P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) restrict brain accumulation of the active sunitinib metabolite N-desethyl sunitinib.	Sunitinib	110-119	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	16-21	
21351087-0	2012	Brain accumulation of sunitinib is restricted by P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) and can be enhanced by oral elacridar and sunitinib coadministration.	Sunitinib	22-31	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	65-70	
21351087-2	2012	We aimed to investigate the in vivo roles of the ATP-binding cassette drug efflux transporters ABCB1 and ABCG2 in plasma pharmacokinetics and brain accumulation of oral sunitinib, and the feasibility of improving sunitinib kinetics using oral coadministration of the dual ABCB1/ABCG2 inhibitor elacridar.	Sunitinib	169-178	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	95-100	
21351087-2	2012	We aimed to investigate the in vivo roles of the ATP-binding cassette drug efflux transporters ABCB1 and ABCG2 in plasma pharmacokinetics and brain accumulation of oral sunitinib, and the feasibility of improving sunitinib kinetics using oral coadministration of the dual ABCB1/ABCG2 inhibitor elacridar.	Sunitinib	213-222	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	95-100	
21351087-2	2012	We aimed to investigate the in vivo roles of the ATP-binding cassette drug efflux transporters ABCB1 and ABCG2 in plasma pharmacokinetics and brain accumulation of oral sunitinib, and the feasibility of improving sunitinib kinetics using oral coadministration of the dual ABCB1/ABCG2 inhibitor elacridar.	Sunitinib	213-222	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	272-277	
26011058-1	2015	Tyrosine kinase inhibitor sunitinib (used in GIST, advanced RCC, and pancreatic neuroendocrine tumors) undergoes CYP3A4 metabolism and is an ABCB1B and ABCG2 efflux transporters substrate.	Sunitinib	26-35	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	141-147	
21309545-8	2011	Furthermore, sunitinib was transported equally by ABCB1 and ABCG2 at low concentrations, but ABCG2-mediated transport became saturated at lower concentrations than ABCB1-mediated transport.	Sunitinib	13-22	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	Mus musculus	50-55