PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23046980-0 2012 Downregulation of miR-223 and miR-153 mediates mechanical stretch-stimulated proliferation of venous smooth muscle cells via activation of the insulin-like growth factor-1 receptor. mir-153 30-37 insulin like growth factor 1 receptor Homo sapiens 143-180 23046980-6 2012 Overexpression of miR-223 or miR-153 down-regulated IGF-1R expression and activity in VSMCs under stretch stress. mir-153 29-36 insulin like growth factor 1 receptor Homo sapiens 52-58 34036380-7 2021 In addition, insulin-like growth factor 1 receptor (IGF1R) was identified as a target of miR-153 in RB cells. mir-153 89-96 insulin like growth factor 1 receptor Homo sapiens 13-50 34036380-7 2021 In addition, insulin-like growth factor 1 receptor (IGF1R) was identified as a target of miR-153 in RB cells. mir-153 89-96 insulin like growth factor 1 receptor Homo sapiens 52-57 34036380-8 2021 More importantly, it was demonstrated that miR-153 upregulation inhibited the expression of its target gene, IGF1R, which inhibited the activation of the Raf/MEK and PI3K/AKT signaling pathways. mir-153 43-50 insulin like growth factor 1 receptor Homo sapiens 109-114 34036380-9 2021 Collectively, the present study demonstrates for the first time, to the best of our knowledge, that miR-153 functions as a tumor suppressor in RB by targeting the IGF1R/Raf/MEK and IGF1R/PI3K/AKT signaling pathways. mir-153 100-107 insulin like growth factor 1 receptor Homo sapiens 163-168 34036380-9 2021 Collectively, the present study demonstrates for the first time, to the best of our knowledge, that miR-153 functions as a tumor suppressor in RB by targeting the IGF1R/Raf/MEK and IGF1R/PI3K/AKT signaling pathways. mir-153 100-107 insulin like growth factor 1 receptor Homo sapiens 181-186