PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35438698-9 2022 Importantly, this effect may be caused by decreased DNMT3a, which in turn downregulates the methylated levels of CPG2 and CPG3 in the Foxp3 promoter region, changing the abundance of Foxp3 expression and improving the Th17/Treg imbalance. treg 223-227 DNA methyltransferase 3A Mus musculus 52-58