PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31584354-9	2019	Furthermore, DEX significantly downregulated the phosphorylation of extracellular-signal-regulated kinase (ERK) 1/2, down-stream effector of MKP3 in CCI mice, whereas the downregulation was reversed by BCI.	Dexmedetomidine	13-16	dual specificity phosphatase 6	Mus musculus	141-145	
31584354-7	2019	DEX markedly elevated the MKP3 expression and modestly reduced the MKP1 expression, with insignificant difference in the latter.	Dexmedetomidine	0-3	dual specificity phosphatase 6	Mus musculus	26-30	
31584354-10	2019	Conclusion: We confirmed that DEX exerts the analgesic effect on chronic neuropathic pain via the regulation of MKP3/ERK1/2 signaling pathway, which may contribute to clarification of the molecular mechanism and novel therapy for chronic neuropathic pain.	Dexmedetomidine	30-33	dual specificity phosphatase 6	Mus musculus	112-116