PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31584354-7 2019 DEX markedly elevated the MKP3 expression and modestly reduced the MKP1 expression, with insignificant difference in the latter. Dexmedetomidine 0-3 dual specificity phosphatase 1 Mus musculus 67-71 35551994-0 2022 Dexmedetomidine protects against acute lung injury in mice via the DUSP1/MAPK/NF-kappaB axis by inhibiting miR-152-3p. Dexmedetomidine 0-15 dual specificity phosphatase 1 Mus musculus 67-72 35551994-12 2022 miR-125-3p overexpression or sh-DUSP1 partially abolished the protection of Dex on MPMVECs. Dexmedetomidine 76-79 dual specificity phosphatase 1 Mus musculus 32-37 35551994-14 2022 sh-DUSP1 partially averted the protection of Dex on MPMVECs. Dexmedetomidine 45-48 dual specificity phosphatase 1 Mus musculus 3-8 35551994-15 2022 Dex inhibited the activation of the MAPK/NF-kappaB pathway in MPMVECs mediated by LPS, which was partially reversed by sh-DUSP1. Dexmedetomidine 0-3 dual specificity phosphatase 1 Mus musculus 122-127 35551994-16 2022 The p38 MAPK inhibitor SB203580 antagonized the protective effect of Dex on MPMVECs mediated by sh-DUSP1. Dexmedetomidine 69-72 dual specificity phosphatase 1 Mus musculus 99-104 35551994-18 2022 CONCLUSION: Dex relieved ALI in mice via the DUSP1/MAPK/NF-kappaB axis by down-regulating miR-152-3p. Dexmedetomidine 12-15 dual specificity phosphatase 1 Mus musculus 45-50