PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31795447-5 2019 Treatment with KPT-9274 (currently in a Phase I trial or analogs, PF3758309 (the PAK4 selective inhibitor) or FK866 (the NAMPT inhibitor)) suppressed the growth of PNET cell lines and synergized with the mammalian target of rapamycin (mTOR) inhibitors everolimus and INK-128. selinexor 15-23 p21 (RAC1) activated kinase 4 Homo sapiens 81-85 31876149-0 2020 KPT-9274, an inhibitor of PAK4 and NAMPT, leads to downregulation of mTORC2 in triple negative breast cancer cells. selinexor 0-8 p21 (RAC1) activated kinase 4 Homo sapiens 26-30 31876149-3 2020 KPT-9274 is a dual specific inhibitor of PAK4 and Nicotinamide Phosphoribosyltransferase (NAMPT). selinexor 0-8 p21 (RAC1) activated kinase 4 Homo sapiens 41-45