PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34284202-0 2021 Antitumor efficacy of XPO1 inhibitor Selinexor in KRAS-mutant lung adenocarcinoma patient-derived xenografts. selinexor 37-46 KRAS proto-oncogene, GTPase Homo sapiens 50-54 35573474-7 2022 KRAS G12C inhibitors in combination with selinexor suppressed the proliferation of KRAS G12C mutant cancer cell lines in a synergistic manner. selinexor 41-50 KRAS proto-oncogene, GTPase Homo sapiens 83-87 35573474-8 2022 Moreover, combined treatment of selinexor with KRAS G12C inhibitors resulted in enhanced spheroid disintegration, reduction in the number and size of colonies formed by G12C mutant cancer cells. selinexor 32-41 KRAS proto-oncogene, GTPase Homo sapiens 47-51 35573474-10 2022 In an in vivo KRAS G12C cell-derived xenograft model, oral administration of a combination of selinexor and sotorasib was demonstrated to reduce tumor burden and enhance survival. selinexor 94-103 KRAS proto-oncogene, GTPase Homo sapiens 14-18 28647672-7 2017 A multicenter phase 1/2 clinical trial of selinexor in previously treated advanced KRAS-mutant NSCLC is under way. selinexor 42-51 KRAS proto-oncogene, GTPase Homo sapiens 83-87