PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24413389-0 2014 Crucial role of heme oxygenase-1 in the sensitivity of acute myeloid leukemia cell line Kasumi-1 to ursolic acid. ursolic acid 100-112 heme oxygenase 1 Homo sapiens 16-32 24413389-4 2014 HO-1 in Kasumi-1 cells was upregulated by being treated with low-dose rather than high-dose UA. ursolic acid 92-94 heme oxygenase 1 Homo sapiens 0-4 24413389-5 2014 Inhibition of HO-1 by zinc protoporphyrin (ZnPP) IX sensitized Kasumi-1 cells to UA, and the apoptotic rate was close to that induced by Ara-C (P<0.01). ursolic acid 81-83 heme oxygenase 1 Homo sapiens 14-18 24413389-7 2014 After silencing HO-1 by siRNA transfection with lentivirus, the cells" proliferation induced by UA was increased as it was by Ara-C. ursolic acid 96-98 heme oxygenase 1 Homo sapiens 16-20 24413389-10 2014 AML-M2 can feasibly be treated by target-inhibiting HO-1 that enhances the antileukemia effects of UA in vitro and in vivo. ursolic acid 99-101 heme oxygenase 1 Homo sapiens 52-56