PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31259152-0 2019 Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88. ursolic acid 0-12 myeloid differentiation primary response gene 88 Mus musculus 105-110 31302461-0 2019 Ursolic acid exhibits anti-inflammatory effects through blocking TLR4-MyD88 pathway mediated by autophagy. ursolic acid 0-12 myeloid differentiation primary response gene 88 Mus musculus 70-75 31259152-14 2019 Meanwhile, the downregulation of MyD88 through the overexpression of miR-149-5p or UA treatment inhibited the activation of the Akt signaling pathway in 231/PTX cells. ursolic acid 83-85 myeloid differentiation primary response gene 88 Mus musculus 33-38 31259152-15 2019 Thus, our data indicate that UA can reverse PTX resistance by targeting the miRNA-149-5p/MyD88 axis in breast cancer cells. ursolic acid 29-31 myeloid differentiation primary response gene 88 Mus musculus 89-94 29735887-7 2018 Pre-treatment of UA also inhibited TLR4/MyD88 signaling activated by LPS. ursolic acid 17-19 myeloid differentiation primary response gene 88 Mus musculus 40-45 21496491-6 2011 Mechanistically, UA markedly inhibited LPS-induced IkappaBalpha phosphorylation and degradation, NF-kappaB p65 nuclear translocation and p38 activation in mouse brain, but did not affect the activation of TLR4, MyD88, ERK, JNK and Akt. ursolic acid 17-19 myeloid differentiation primary response gene 88 Mus musculus 211-216 25213465-5 2014 Ursolic acid not only inhibited the Alexa Fluor 488-conjugated LPS-mediated shift of macrophages but also reduced the intensity of fluorescent LPS bound to the macrophages transiently transfected with or without MyD88 siRNA. ursolic acid 0-12 myeloid differentiation primary response gene 88 Mus musculus 212-217