PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29098660-3	2017	The biological effects of ursolic acid have been evaluated in vitro, in different cell types and against several toxic insults (i.e. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, amyloid-beta peptides, kainic acid and others); in animal models of brain-related disorders (Alzheimer disease, Parkinson disease, depression, traumatic brain injury) and ageing; and in clinical studies with cancer patients and for muscle atrophy.	ursolic acid	26-38	amyloid beta precursor protein	Homo sapiens	179-191	
34902447-0	2022	Ursolic acid ameliorates amyloid beta-induced pathological symptoms in Caenorhabditis elegans by activating the proteasome.	ursolic acid	0-12	amyloid beta precursor protein	Homo sapiens	25-37	
34902447-14	2022	CONCLUSIONS: Our study revealed that ursolic acid prevented amyloid beta-induced proteotoxic stress, specifically by reducing the amount of amyloid beta and increasing proteasome activity in vivo.	ursolic acid	37-49	amyloid beta precursor protein	Homo sapiens	60-72	
34902447-14	2022	CONCLUSIONS: Our study revealed that ursolic acid prevented amyloid beta-induced proteotoxic stress, specifically by reducing the amount of amyloid beta and increasing proteasome activity in vivo.	ursolic acid	37-49	amyloid beta precursor protein	Homo sapiens	140-152	
34902447-15	2022	Furthermore, the therapeutic effect of ursolic acid on transgenic nematodes expressing amyloid beta depended on the increased activity of the proteasome.	ursolic acid	39-51	amyloid beta precursor protein	Homo sapiens	87-99	
34902447-10	2022	RESULTS: In our study, ursolic acid successfully repressed amyloid beta-induced paralysis and hypersensitivity to serotonin in Caenorhabditis elegans.	ursolic acid	23-35	amyloid beta precursor protein	Homo sapiens	59-71	
34902447-11	2022	The levels of amyloid beta monomers, oligomers, and deposits were decreased after treatment with ursolic acid in transgenic nematodes overexpressing human amyloid beta; however, ursolic acid did not affect exogenous transgene transcription and expression levels.	ursolic acid	97-109	amyloid beta precursor protein	Homo sapiens	14-26	
34902447-11	2022	The levels of amyloid beta monomers, oligomers, and deposits were decreased after treatment with ursolic acid in transgenic nematodes overexpressing human amyloid beta; however, ursolic acid did not affect exogenous transgene transcription and expression levels.	ursolic acid	97-109	amyloid beta precursor protein	Homo sapiens	155-167	
34902447-11	2022	The levels of amyloid beta monomers, oligomers, and deposits were decreased after treatment with ursolic acid in transgenic nematodes overexpressing human amyloid beta; however, ursolic acid did not affect exogenous transgene transcription and expression levels.	ursolic acid	178-190	amyloid beta precursor protein	Homo sapiens	14-26