PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34259316-8	2021	Compared with those in the DSS group, the expressions of IL-1beta, IL-6, IL-17, and TNF-alpha in the DSS+DHA and DSS+5-aminosalicylic acid (5-ASA) groups were decreased, while the expressions of IL-4 and IL-10 were significantly upregulated.	artenimol	105-108	interleukin 6	Homo sapiens	67-71	
34755560-1	2021	OBJECTIVE: To explore whether dihydroartemisinin (DHA) can block interleukin (IL)-6-induced epithelial-mesenchymal transition (EMT) in laryngeal squamous cell carcinoma (LSCC).	artenimol	30-48	interleukin 6	Homo sapiens	65-83	
34755560-1	2021	OBJECTIVE: To explore whether dihydroartemisinin (DHA) can block interleukin (IL)-6-induced epithelial-mesenchymal transition (EMT) in laryngeal squamous cell carcinoma (LSCC).	artenimol	50-53	interleukin 6	Homo sapiens	65-83	
34755560-6	2021	Furthermore, DHA upregulated miR-130b-3p, which can downregulate STAT3 and beta-catenin protein expression and decrease the activity of the IL-6/STAT3 signaling pathway.	artenimol	13-16	interleukin 6	Homo sapiens	140-144	
34755560-8	2021	CONCLUSIONS: DHA can block IL-6-triggered EMT and invasion in LSCC, and during these processes, DHA increases miR-130b-3p expression to decrease the activation of the IL-6/STAT3 and beta-catenin signaling pathways.	artenimol	13-16	interleukin 6	Homo sapiens	27-31	
34755560-8	2021	CONCLUSIONS: DHA can block IL-6-triggered EMT and invasion in LSCC, and during these processes, DHA increases miR-130b-3p expression to decrease the activation of the IL-6/STAT3 and beta-catenin signaling pathways.	artenimol	13-16	interleukin 6	Homo sapiens	167-171	
34755560-8	2021	CONCLUSIONS: DHA can block IL-6-triggered EMT and invasion in LSCC, and during these processes, DHA increases miR-130b-3p expression to decrease the activation of the IL-6/STAT3 and beta-catenin signaling pathways.	artenimol	96-99	interleukin 6	Homo sapiens	27-31	
34755560-8	2021	CONCLUSIONS: DHA can block IL-6-triggered EMT and invasion in LSCC, and during these processes, DHA increases miR-130b-3p expression to decrease the activation of the IL-6/STAT3 and beta-catenin signaling pathways.	artenimol	96-99	interleukin 6	Homo sapiens	167-171	
32425545-9	2020	We found that M2-like TAMs promoted the invasion, migration, and angiogenesis of HNSCC cells; however, DHA significantly inhibited IL-4/IL-6-induced M2 macrophage polarization.	artenimol	103-106	interleukin 6	Homo sapiens	136-140	
35059772-8	2022	RESULTS: In the present study, we found that DHA significantly suppressed AngII-induced proliferation of VSMCs and the expression of IL-6 and Ccl2 in a dose-dependent manner.	artenimol	45-48	interleukin 6	Homo sapiens	133-137	
32892075-7	2020	Additionally, DHA in vivo improved the clinical symptoms, reduced the production of pro-inflammatory factors IL-1beta, IL-6 and TNF-alpha, and suppressed the formation of NLRP3 inflammasome.	artenimol	14-17	interleukin 6	Homo sapiens	119-123