PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31708778-0	2019	Eupafolin Suppresses Esophagus Cancer Growth by Targeting T-LAK Cell-Originated Protein Kinase.	eupafolin	0-9	PDZ binding kinase	Homo sapiens	58-94	
31708778-4	2019	Nowadays, we found that eupafolin suppressed TOPK activities at the first time in vitro and in vivo.	eupafolin	24-33	PDZ binding kinase	Homo sapiens	45-49	
31708778-6	2019	Furthermore, knockdown of TOPK in KYSE450 cells decreased their sensitivities to eupafolin.	eupafolin	81-90	PDZ binding kinase	Homo sapiens	26-30	
31708778-9	2019	To sum up, eupafolin as an TOPK inhibitor can suppress growth of esophagus cancer in vitro and in vivo.	eupafolin	11-20	PDZ binding kinase	Homo sapiens	27-31	
31708778-10	2019	The TOPK downstream signaling molecule histone H3 in tumor tissues was also reduced after eupafolin treatment.	eupafolin	90-99	PDZ binding kinase	Homo sapiens	4-8	
31708778-11	2019	In short, eupafolin can suppress growth of esophagus cancer cells as an TOPK inhibitor both in vitro and in vivo.	eupafolin	10-19	PDZ binding kinase	Homo sapiens	72-76