PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27414646-4	2016	Eupafolin inhibited the LPS-induced phosphorylation of p38 MAPK, ERK1/2, JNK, AKT and p65 and the nuclear translocation of p65 and c-fos.	eupafolin	0-9	thymoma viral proto-oncogene 1	Mus musculus	78-81	
24700667-0	2015	Eupafolin suppresses prostate cancer by targeting phosphatidylinositol 3-kinase-mediated Akt signaling.	eupafolin	0-9	thymoma viral proto-oncogene 1	Mus musculus	89-92	
24700667-5	2015	Protein content analysis indicated that phosphorylation of Akt and its downstream kinases was inhibited by eupafolin treatment.	eupafolin	107-116	thymoma viral proto-oncogene 1	Mus musculus	59-62	
24212072-0	2014	Eupafolin, a skin whitening flavonoid isolated from Phyla nodiflora, downregulated melanogenesis: Role of MAPK and Akt pathways.	eupafolin	0-9	thymoma viral proto-oncogene 1	Mus musculus	115-118	
25975517-7	2015	RESULTS: Eupafolin pretreatment reduced the TNF-alpha-induced ICAM-1 expression and also the ERK1/2, JNK, p38, and AKT/PI3K phosphorylation.	eupafolin	9-18	thymoma viral proto-oncogene 1	Mus musculus	115-118	
25975517-11	2015	CONCLUSIONS: Eupafolin exerts its anti-inflammatory activity by suppressing the TNF-alpha-induced ICAM-1 expression and subsequent monocyte adhesion via AKT/ERK1/2/JNK phosphorylation and nuclear translocation of NF-kappaB p65.	eupafolin	13-22	thymoma viral proto-oncogene 1	Mus musculus	153-156	
24212072-9	2014	In addition, eupafolin significantly induced the phosphorylation of ERK1/2 and p38 MAPK, whereas the decreased effect was observed in the phosphorylation of Akt.	eupafolin	13-22	thymoma viral proto-oncogene 1	Mus musculus	157-160	
24212072-11	2014	CONCLUSIONS: Our results seem that inhibition of Akt and activation of phospho-ERK or p38 MAPK may lead to the suppression of melanogenesis in eupafolin-treated B16F10 mouse melanoma cells.	eupafolin	143-152	thymoma viral proto-oncogene 1	Mus musculus	49-52