PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31442404-2	2019	Here we show that, in the mammalian small intestine, the expression of Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthetase 2), the gene encoding the rate-limiting enzyme in the production of ketone bodies, including beta-hydroxybutyrate (betaOHB), distinguishes self-renewing Lgr5+ stem cells (ISCs) from differentiated cell types.	betaohb	236-243	NFS1 cysteine desulfurase	Homo sapiens	292-296	
31442404-3	2019	Hmgcs2 loss depletes betaOHB levels in Lgr5+ ISCs and skews their differentiation toward secretory cell fates, which can be rescued by exogenous betaOHB and class I histone deacetylase (HDAC) inhibitor treatment.	betaohb	21-28	NFS1 cysteine desulfurase	Homo sapiens	45-49	
31442404-3	2019	Hmgcs2 loss depletes betaOHB levels in Lgr5+ ISCs and skews their differentiation toward secretory cell fates, which can be rescued by exogenous betaOHB and class I histone deacetylase (HDAC) inhibitor treatment.	betaohb	145-152	NFS1 cysteine desulfurase	Homo sapiens	45-49	
31442404-6	2019	These findings reveal how control of betaOHB-activated signaling in ISCs by diet helps to fine-tune stem cell adaptation in homeostasis and injury.	betaohb	37-44	NFS1 cysteine desulfurase	Homo sapiens	68-72