PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34186009-7	2021	Mice treated with AST showed slower memory decline and decreased depositions of amyloid-beta (Abeta) and tau protein.	astaxanthine	18-21	amyloid beta (A4) precursor protein	Mus musculus	94-99	
32944864-4	2021	Moreover, mTOR activation perturbed the mitochondrial dynamics, increased the synaptic plasticity after 21 days of treatment with Ast (10 mg/kg/day), and increased the expression of Abeta-degrading enzymes, mitochondrial fusion, and synapse-associated proteins and decreased the expression of mitochondrial fission proteins.	astaxanthine	130-133	amyloid beta (A4) precursor protein	Mus musculus	182-187	
32944864-8	2021	Graphical abstract In summary, Ast ameliorates cognitive deficits via facilitating the mTOR-dependent mitochondrial dynamics and synaptic damage, and reducing Abeta accumulation.	astaxanthine	31-34	amyloid beta (A4) precursor protein	Mus musculus	159-164