PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21686277-6 2011 Moreover, inhibition of JNK by SP600125 rescued PC12 cells from Chp-triggered cell death and attenuated activation of caspases-9 and -3/7 suggesting that activation of JNK mediates pro-apoptotic effect of Chp. pyrazolanthrone 31-39 caspase 9 Rattus norvegicus 118-135 12869386-10 2003 SP-600125, a specific inhibitor of JNK activation, prevented cytochrome c release from mitochondria, JNK activation, DNA fragmentation, and caspase-9 activation in response to TNF-alpha/CHX. pyrazolanthrone 0-9 caspase 9 Rattus norvegicus 140-149 24294888-8 2014 VPA also inhibited cytochrome c release and caspase-9 activation, which was significantly inhibited by SP600125, a JNK inhibitor. pyrazolanthrone 103-111 caspase 9 Rattus norvegicus 44-53 18569012-5 2008 The JNK inhibitor SP600125 attenuated the activation of caspase-9 and -3 and reduced 25-OH-chol-induced cell death. pyrazolanthrone 18-26 caspase 9 Rattus norvegicus 56-72